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Pierce's Disease
Research Updates

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What is Pierce's Disease?

Pierce's Disease is a bacterial infection, which is spread by bugs that feed on grapevines, particularly the "glassy winged sharpshooter." Grapevines that become infected with PD can quickly become sick and die.

glassy-winged sharpshooter

EXPLOITING XYLELLA FASTIDIOSA PROTEINS FOR PIERCES DISEASE CONTROL

  • Author(s): Bruening, George; Civerolo, Ed; Dandekar, Abhaya; Feldstein, Paul; Francis, Marta; Gupta, Goutam;
  • Abstract: The aim of this project is to construct and express in test plants, and then in grapevine, a protein or protein chimera (anti-Xf protein) capable of inactivating or otherwise interfering with the infectivity of Xylella fastidiosa (Xf), the causative agent of Pierces disease of grapevine. Several Xf-cell-surface-binding peptides were selected from a random peptide library. For some of these peptides, the Xf cell target of binding and the stoichiometry of binding have been tentative identified. Evidence was obtained for a biologically relevant interaction between the selected peptides and Xf cells.
  • Publication Date: Nov 2006
  • Journal: 2006 Pierce's Disease Research Symposium

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