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Pierce's Disease
Research Updates

piercesdisease.cdfa.ca.gov

What is Pierce's Disease?

Pierce's Disease is a bacterial infection, which is spread by bugs that feed on grapevines, particularly the "glassy winged sharpshooter." Grapevines that become infected with PD can quickly become sick and die.

glassy-winged sharpshooter

[Anti-lipoperoxidation of grape seed extracts in vitro]

  • Author(s): Cai, X.; Chen, Q.; Guo, Y.; Li, W.;
  • Abstract: The anti-lipoperoxidation of grape seed extracts (GSE) was observed by malondialdehyde (MDA) generated in liver and brain homogeneates spontaneously or induced by CCl4, H2O2, Fe(2+)-ascorbic acid. The exhaustion of glutathione (GSH) in liver homogenate initiated by Fe(2+)-ascorbic acid was also tested. Results showed that GSE significantly inhibited the generation of MDA in rat liver and brain homogenates both spontaneously formed or induced by CCl4, H2O2 and Fe(2+)-ascorbic acid with dose-effect relationships. GSE could also reduce the exhaustion of GSH levels in mice liver. The study indicated that GSE is effective on the inhibition of lipid peroxide and on the protection of liver from injury caused by lipid peroxidation.
  • Publication Date: Feb 2002
  • Journal: Wei Sheng Yan Jiu

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